Wikipedia

FAH

FAH (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[15][16]

FAH
Нинди таксонда бар H. sapiens[d][1]
Кодлаучы ген FAH[d][1]
Молекуляр функция fumarylacetoacetase activity[d][2][3][3][…], связывание с белками плазмы[d][4], активность катализатора[d][5], гидролазная активность[d][5], связывание с ионом металла[d][5], fumarylacetoacetase activity[d][2][3][3][…] һәм fumarylacetoacetase activity[d][6][5][5][…]
Күзәнәк компоненты цитозоль[d][5], экзосома[d][7][8][9], цитозоль[d][5][10] һәм экзосома[d][11][12]
Биологик процесс aromatic amino acid family metabolic process[d][5], Метаболизм[3], L-phenylalanine catabolic process[d][3][3], arginine catabolic process[d][5], tyrosine catabolic process[d][13][3], L-phenylalanine catabolic process[d][5][5][10], tyrosine catabolic process[d][14][5][10] һәм homogentisate catabolic process[d][10]
Изображение Gene Atlas

Искәрмәләр

үзгәртү
  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,0 2,1 D Phaneuf, Y Labelle, D Bérubé et al. Cloning and expression of the cDNA encoding human fumarylacetoacetate hydrolase, the enzyme deficient in hereditary tyrosinemia: assignment of the gene to chromosome 15, Cloning and expression analysis of a cDNA encoding fumarylacetoacetate hydrolase: post-transcriptional modulation in rat liver and kidney // Am. J. Hum. Genet. — Cell Press, Elsevier BV, 1991. — ISSN 0002-9297; 1537-6605 — doi:10.1016/0378-1119(91)90250-F — PMID:1998338; PMID:1916290
  3. ↑ 3,0 3,1 3,2 3,3 3,4 3,5 3,6 3,7 GOA
  4. ↑ Dricot A., Barabási A., Tavernier J. et al. A proteome-scale map of the human interactome network // Cell — Cell Press, Elsevier BV, 2014. — ISSN 0092-8674; 1097-4172 — doi:10.1016/J.CELL.2014.10.050 — PMID:25416956
  5. ↑ 5,00 5,01 5,02 5,03 5,04 5,05 5,06 5,07 5,08 5,09 5,10 5,11 GOA
  6. ↑ D Phaneuf, Y Labelle, D Bérubé et al. Cloning and expression of the cDNA encoding human fumarylacetoacetate hydrolase, the enzyme deficient in hereditary tyrosinemia: assignment of the gene to chromosome 15, Cloning and expression analysis of a cDNA encoding fumarylacetoacetate hydrolase: post-transcriptional modulation in rat liver and kidney // Am. J. Hum. Genet. — Cell Press, Elsevier BV, 1991. — ISSN 0002-9297; 1537-6605 — doi:10.1016/0378-1119(91)90250-F — PMID:1998338; PMID:1916290
  7. ↑ Farina A., Lane L., Lescuyer P. et al. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine // Journal of Proteomics — Elsevier BV, 2013. — ISSN 1874-3919; 0165-022X — doi:10.1016/J.JPROT.2013.01.012 — PMID:23376485
  8. ↑ Pisitkun T., Tchapyjnikov D., Knepper M. A. Large-scale proteomics and phosphoproteomics of urinary exosomes // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2008040406 — PMID:19056867
  9. ↑ Sinha A., Kislinger T. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine // Proteomics / L. Stimson — Wiley, 2013. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.201200561 — PMID:23533145
  10. ↑ 10,0 10,1 10,2 10,3 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  11. ↑ Pisitkun T., Tchapyjnikov D., Knepper M. A. Large-scale proteomics and phosphoproteomics of urinary exosomes // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2008040406 — PMID:19056867
  12. ↑ Sinha A., Kislinger T. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine // Proteomics / L. Stimson — Wiley, 2013. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.201200561 — PMID:23533145
  13. ↑ J. Miyazaki Complete rescue of lethal albino c14CoS mice by null mutation of 4-hydroxyphenylpyruvate dioxygenase and induction of apoptosis of hepatocytes in these mice by in vivo retrieval of the tyrosine catabolic pathway, Complete Rescue of Lethal Albino c Mice by Null Mutation of 4-Hydroxyphenylpyruvate Dioxygenase and Induction of Apoptosis of Hepatocytes in These Mice by in VivoRetrieval of the Tyrosine Catabolic Pathway // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1997. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.272.39.24426 — PMID:9305902
  14. ↑ J. Miyazaki Complete rescue of lethal albino c14CoS mice by null mutation of 4-hydroxyphenylpyruvate dioxygenase and induction of apoptosis of hepatocytes in these mice by in vivo retrieval of the tyrosine catabolic pathway, Complete Rescue of Lethal Albino c Mice by Null Mutation of 4-Hydroxyphenylpyruvate Dioxygenase and Induction of Apoptosis of Hepatocytes in These Mice by in VivoRetrieval of the Tyrosine Catabolic Pathway // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1997. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.272.39.24426 — PMID:9305902
  15. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
  16. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

үзгәртү
  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


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