TCIRG1 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[12][13]

TCIRG1
Нинди таксонда бар H. sapiens[d][1]
Кодлаучы ген TCIRG1[d][1]
Молекуляр функция transporter activity[d][2], ATPase binding[d][3], proton-transporting ATPase activity, rotational mechanism[d][3] һәм proton transmembrane transporter activity[d][4]
Күзәнәк компоненты мембрана өлеше[d][4], proton-transporting V-type ATPase, V0 domain[d][4], phagocytic vesicle membrane[d][5], мембрана[d][4], vacuolar proton-transporting V-type ATPase, V0 domain[d][4], күзәнәк мембранасы[d][5][6][5], күзәнәк мембранасы өлеше[d][7], lysosomal membrane[d][8], apical plasma membrane[d][9], митохондрия[5], vacuolar proton-transporting V-type ATPase complex[d][3], endosome membrane[d][4], ficolin-1-rich granule membrane[d][4], lysosomal membrane[d][10], күзәнәк мембранасы[d][4][11][4][…], төш[4], лизосома[4], late endosome[d][4], secretory granule membrane[d][4], phagocytic vesicle membrane[d][4][4] һәм phagocytic vesicle[d][4]
Биологик процесс protein catabolic process in the vacuole[d][4][4], insulin receptor signaling pathway[d][4], transferrin transport[d][4], vacuolar proton-transporting V-type ATPase complex assembly[d][5], ion transport[d][4], vacuolar acidification[d][3], cellular defense response[d][11], ion transmembrane transport[d][4], позитивная регуляция пролиферации клеток[d][11], ATP synthesis coupled proton transport[d][5], macroautophagy[d][4][4], phagosome acidification[d][5], neutrophil degranulation[d][4], перенос[d][5], proton transmembrane transport[d][2], оссификация[d][4], osteoclast proliferation[d][4], immunoglobulin production[d][4], cellular calcium ion homeostasis[d][4], апоптоз[d][4], воспалительная реакция[d][4], regulation of proton transport[d][4], response to silver ion[d][4], Регуляция экспрессии генов[d][4], immunoglobulin mediated immune response[d][4], optic nerve development[d][4], myeloid cell differentiation[d][4], B cell differentiation[d][4], T cell differentiation[d][4], osteoclast differentiation[d][4], memory T cell activation[d][4], T-helper 1 cell activation[d][4], odontogenesis[d][4], T cell homeostasis[d][4], tooth eruption[d][4], костная резорбция[d][4], regulation of osteoblast differentiation[d][4], pH reduction[d][4], homeostasis of number of cells[d][4], regulation of insulin secretion[d][4], retina development in camera-type eye[d][4], hematopoietic stem cell homeostasis[d][4], enamel mineralization[d][4], cellular response to cytokine stimulus[d][4], phagosome acidification[d][4][4] һәм dentin mineralization[d][4]

Искәрмәләр

үзгәртү
  1. 1,0 1,1 UniProt
  2. 2,0 2,1 Li Y. P., W Chen, P Stashenko Molecular cloning and characterization of a putative novel human osteoclast-specific 116-kDa vacuolar proton pump subunit // Biochem. Biophys. Res. Commun.Academic Press, Elsevier BV, 1996. — ISSN 0006-291X; 1090-2104doi:10.1006/BBRC.1996.0145PMID:8579597
  3. 3,0 3,1 3,2 3,3 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform.OUP, 2011. — ISSN 1467-5463; 1477-4054doi:10.1093/BIB/BBR042PMID:21873635
  4. 4,00 4,01 4,02 4,03 4,04 4,05 4,06 4,07 4,08 4,09 4,10 4,11 4,12 4,13 4,14 4,15 4,16 4,17 4,18 4,19 4,20 4,21 4,22 4,23 4,24 4,25 4,26 4,27 4,28 4,29 4,30 4,31 4,32 4,33 4,34 4,35 4,36 4,37 4,38 4,39 4,40 4,41 4,42 4,43 4,44 4,45 4,46 4,47 4,48 4,49 4,50 4,51 4,52 4,53 4,54 4,55 4,56 GOA
  5. 5,0 5,1 5,2 5,3 5,4 5,5 5,6 5,7 GOA
  6. N Utku, T Heinemann, Tullius S. G. et al. Prevention of acute allograft rejection by antibody targeting of TIRC7, a novel T cell membrane protein // ImmunityCell Press, Elsevier BV, 1998. — ISSN 1074-7613; 1097-4180doi:10.1016/S1074-7613(00)80634-2PMID:9806637
  7. T Heinemann, Bulwin G. C., J Randall et al. Genomic organization of the gene coding for TIRC7, a novel membrane protein essential for T cell activation // Genomics / A. EngelAcademic Press, Elsevier BV, 1999. — ISSN 0888-7543; 1089-8646doi:10.1006/GENO.1999.5751PMID:10329006
  8. Schröder B., Wrocklage C., Pan C. et al. Integral and associated lysosomal membrane proteins // TrafficWiley-Blackwell, 2007. — ISSN 1398-9219; 1600-0854doi:10.1111/J.1600-0854.2007.00643.XPMID:17897319
  9. Devuyst O., Karet F. E., Villa A. et al. Vacuolar H+-ATPase d2 subunit: molecular characterization, developmental regulation, and localization to specialized proton pumps in kidney and bone // Journal of the American Society of Nephrology / J. BriggsAmerican Society of Nephrology, 2005. — ISSN 1046-6673; 1533-3450doi:10.1681/ASN.2004090761PMID:15800125
  10. Schröder B., Wrocklage C., Pan C. et al. Integral and associated lysosomal membrane proteins // TrafficWiley-Blackwell, 2007. — ISSN 1398-9219; 1600-0854doi:10.1111/J.1600-0854.2007.00643.XPMID:17897319
  11. 11,0 11,1 11,2 N Utku, T Heinemann, Tullius S. G. et al. Prevention of acute allograft rejection by antibody targeting of TIRC7, a novel T cell membrane protein // ImmunityCell Press, Elsevier BV, 1998. — ISSN 1074-7613; 1097-4180doi:10.1016/S1074-7613(00)80634-2PMID:9806637
  12. HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
  13. UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

үзгәртү
  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)